stickdog99 wrote:A select few people die of the flu. What is the news story here?
This flu kills healthy people by turning their healthy immune systems against them. It is not like a normal flu, that kills sickly people. We are one mutation away from all hell breaking loose.
H1N1 flu may induce a 'cytokine storm'
SARANAC LAKE, N.Y., May 6 (UPI) -- The H1N1 flu may be dangerous for healthy, young adults because it contains genetic components of the H5N1 avian influenza virus, U.S. researchers say.
The flu contains genetic components of the H5N1 avian influenza virus, which can induce a "cytokine storm," in which a patient's hyperactivated immune system causes potentially fatal damage to the lungs.
David L. Woodland, editor in chief of Viral Immunology and president of Trudeau Institute Inc. in Saranac Lake, N.Y., says a cytokine storm occurs when the body's immune system overreacts to an intruder, such as a virus, by producing high levels of cytokines, which are signaling chemicals that help mobilize immune cells capable of removing infectious agents from the body.
When too many cytokines are produced, they can stimulate an inflammatory response in which the accumulation of immune cells and fluid at the site of infection may prevent affected tissues and organs such as the lungs from functioning properly and may cause death, Woodland says.
What is known is that some H1N1 viruses have pandemic potential and that historical evidence supports the possibility that healthy young adults may be especially susceptible to more severe infection and poor outcomes due to the ability of a strong immune system to initiate a cytokine storm, Woodland adds.
FWIW:
Nicotine, Anti-inflammatory H1N1 Cure
Nicotine has an anti-inflammatory effect via the vagus nerve, which is useful against many diseases, and perhaps may block the cytokine storm of the H1N1 swine flu.
Nicotine stimulates the cholinergic anti-inflammatory pathway. At the end of this pathway are immune cells that produce anti-inflammatory cytokines that block inflammation. Thus, nicotine, although one of the most addictive chemicals, can have beneficial effects on inflammatory diseases, such as arthritis, asthma, cancer, inflammatory bowel diseases and perhaps, H1N1.
Tobacco Smoke Is Toxic but also Anti-Inflammatory
Paradoxically tobacco smoke contains hundreds of toxic and carcinogenic chemicals that produce inflammatory reactions and numerous degenerative diseases, but it also contains nicotine that is anti-inflammatory. Smokers assault their bodies, but moderate and obscure the inflammatory degeneration and disease, until they stop the nicotine exposure.
Nicotine Withdrawal Is Inflammatory
The anti-inflammatory benefits of nicotine reveal the inflammatory basis of many unexpected diseases. Nicotine withdrawal is severe, partly because it leads to rebound release of inflammatory cytokines, inflammation and inflammatory disease symptoms that include depression and obesity.
Nicotine Acts via the Vagus Nerve
Attempts to augment bypass surgery for weight reduction have encountered the anti-inflammatory benefits of stimulating the vagus nerve. Vagus nerve stimulation via an electrode attached to the left branch in the neck by a device implanted behind the clavicle, reduces inflammatory cytokine production and is an effective treatment for obesity. Other types of vagus stimulation are being tested for efficacy in treatment of numerous inflammatory diseases, including arthritis, allergy, asthma, Alzheimer’s, etc.
Nicotine Blocks Cytokine Storms
Cytokine storms are a deadly consequence of inflammation that is out of control. These exaggerated host responses are targets for bioterrorism, because it takes very little toxin or a very minimal infection to be lethal, if it produces a cytokine storm. In mice, the ricin toxin, a bioterrorism agent, induces a cytokine storm that kills by multiple organ failure. Ricin-treated mice can be protected by nicotine prior or after the cytokine storm begins.
H1N1 May Kill by Cytokine Storm Similar to Spanish Flu of 1918
The rapid high temperature produced by Mexican H1N1 suggest that some of the deaths have resulted from cytokine storms. As more information becomes available on existing cases, it will become more clear how similar the current H1N1 strain is to the virus that caused the Spanish flu pandemic of 1918.
Block H1N1 Cytokine Storms with Nicotine
It may be possible to reduce lethality by blocking the cytokine storm with nicotine. There are numerous means of administering nicotine and research will need to be done to determine which if any of these approaches is effective in the treatment of severe cases of the current H1N1 flu.

