DIY Biohackers Are Editing Genes in Garages and Kitchens

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DIY Biohackers Are Editing Genes in Garages and Kitchens

Postby Grizzly » Mon Oct 23, 2017 12:22 pm

DIY Biohackers Are Editing Genes in Garages and Kitchens
http://reason.com/reasontv/2017/10/18/d ... es-garages

With the latest breakthroughs in the life sciences, who needs a lab or degree?




"A biohacker for me is somebody who is doing something clever or interesting in biology," says Josiah Zayner, a molecular biophysicist who runs The ODIN, a company that sells do-it-yourself genetic engineering kits. "They're usually these people that have been fucked by the system who are trying to unfuck themselves."

Zayner is one of the leading figures in the biohacking movement and is the main organizer of the BioHack the Planet Conference, a yearly gathering of citizen scientists. This year, over 100 members of the biohacking community met in Oakland, California to discuss a wide array of issues from at-home genetic engineering to questions on bioethics.

Biohackers have often been compared to computer hackers of the 1980s, but instead of breaking into and manipulating information technology systems, they're focused on hacking living organisms with the hopes of curing illnesses and in some cases obtaining superhuman powers.

Their shared mission is to put this technology into the hands of as many people as possible.

"People should be able to use all the technologies that science develops," says Zayner. "It shouldn't just be patented and given to companies or exclusively given to certain people."

These do-it-yourself biologists say the democratization of science has given them the freedom to do work on projects that are often ignored by larger institutions. They're using gene editing technologies like CRISPR to create personalized treatments for those suffering from rare diseases or cancer, reverse engineering pharmaceuticals like Epi-Pens so people can make their own medicine at home, and even creating glow in the dark beer.

"I think this is the most exciting time thus far in the history of the world to be alive with respect to what we can and will do with life forms," says Hank Greely, the director of the Center for Law and the Biosciences at Stanford University.

But breakthroughs in the world of biohacking are drawing more scrutiny from federal regulators. Earlier this year, the Food and Drug Administration began placing restrictions on non-human genetic modifications and declared that genetically edited animals must be classified as drugs. This gives the agency broad authority over a number of do-it-yourself genetics tests and requires experiments involving animals to go through the same vetting process as a new drug.

"I guess they couldn't call them cosmetics and they couldn't call them foods, so they're like dogs are drugs," states David Ishee, a Mississippi canine breeder who is working on editing out genetic diseases in dogs. "Everybody's worried about what someone could do with this technology and nobody seems to care about the damage that not doing it will cause because these animals are dying."

Increasing regulation could undermine biohacking breakthroughs for humans as well.

"I'm a huge fan of deregulation because I believe in the inherent goodness of capitalism," says Zayner. "Stuff doesn't progress unless people do useful things with it."

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Re: DIY Biohackers Are Editing Genes in Garages and Kitchens

Postby DrEvil » Mon Oct 23, 2017 4:25 pm

"I'm a huge fan of deregulation because I believe in the inherent goodness of capitalism," says Zayner.


Oh, you sweet summer child. Too much Rand-Aid.

I like what these guys are doing, but some regulation is inevitable, and probably necessary. You can do good with this stuff, but you can also do some serious harm when some random guy with a basement lab has the ability to recreate smallpox, and even modify it. All it takes is one lunatic who truly believes that Earth would be better off without humans.
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Re: DIY Biohackers Are Editing Genes in Garages and Kitchens

Postby Asta » Mon Oct 23, 2017 4:30 pm

It's time to reread "Oryx and Crake".
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Re: DIY Biohackers Are Editing Genes in Garages and Kitchens

Postby Iamwhomiam » Mon Oct 23, 2017 5:53 pm

Indeed, Asta!

If you think gun regulation is tough to get passed, wait until they try to regulate genetic research! Without restricting access to the crisper gene, which is all but impossible now, it will be impossible to enforce were it to pass into law.
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Re: DIY Biohackers Are Editing Genes in Garages and Kitchens

Postby DrEvil » Mon Oct 23, 2017 6:32 pm

^^I think regulating genetic research would be way easier than guns. Just shout something about "messing with God's Creation" and "Designer Babies" and there you go. It will never be completely banned, unless we get some real horror stories out of it, but I don't see the bible thumping loonies in the republican party getting very enthusiastic about it either (other than in a "the rapture is near. Praise God!" way). We've had people blowing up abortion clinics for decades. It's only a matter of time before they start targeting genetic researchers.

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Re: DIY Biohackers Are Editing Genes in Garages and Kitchens

Postby Iamwhomiam » Mon Oct 23, 2017 7:12 pm

Yeah, but... How successful were they in preventing Alaskan Thunder Fuck or Blueberry Shazam or any of the thousands of other fine strains of weed from being developed? All such research was then forbidden.

My thinking is more along the lines of fearing that one sick kid in the neighborhood who enjoyed dismembering all sorts of creatures before killing them who also happened to have a genius IQ - who in future times will be creating all sorts of living abominations to toy with according to his psychotic whimsy.

All sorts of things to aerosolize and subjects enough test their efficacy upon. Besides, Typhoid Mary's are so 20th century and today, not so easily detectable.

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Re: DIY Biohackers Are Editing Genes in Garages and Kitchens

Postby DrEvil » Mon Oct 23, 2017 8:49 pm

Ah, that makes sense. I misunderstood your meaning. Absolutely - the genie is out of the bottle, and anyone with a modicum of knowledge can now set up their own research lab, regulations be damned. Everything you need to become a microbiologist is available as free online courses, old lab equipment can be bought on auction, etc. All you really need is dedication and discretion.
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Re: DIY Biohackers Are Editing Genes in Garages and Kitchens

Postby OP ED » Wed Oct 25, 2017 2:14 am

Iamwhomiam » Mon Oct 23, 2017 6:12 pm wrote:Yeah, but... How successful were they in preventing Alaskan Thunder Fuck or Blueberry Shazam or any of the thousands of other fine strains of weed from being developed? All such research was then forbidden.

My thinking is more along the lines of fearing that one sick kid in the neighborhood who enjoyed dismembering all sorts of creatures before killing them who also happened to have a genius IQ - who in future times will be creating all sorts of living abominations to toy with according to his psychotic whimsy.

All sorts of things to aerosolize and subjects enough test their efficacy upon. Besides, Typhoid Mary's are so 20th century and today, not so easily detectable.

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