Here is the actual Nature study that shows than the mRNA vaccines that were forced on all of us were using an inherently flawed technology.
And is here is my response to Science's attempt to soften the blow of what the study published in Nature showed:
mRNA vaccines may make unintended proteins, but there’s no evidence of harm
Alterations that help messenger RNA persist in living cells can trip up protein synthesis
Even after the billions of doses given during the pandemic, messenger RNA (mRNA) vaccines still hold surprises.
LOL! SURPRISE! SURPRISE! SURPRISE! Your body made the wrong protein because the mRNA technology that you injected yourself with over and over and over was inherently flawed!!!
A study out today reveals they may unexpectedly prompt cells to produce small amounts of unintended proteins.
LOL! SURPRISE! Don't worry that your body made the wrong protein because the mRNA technology that you injected yourself with over and over and over was inherently flawed because it was only in "small amounts"! Trust us! We are Science, so we are being very scientific by using such precise language!
There is no evidence that these mistakes compromise the safety of the COVID-19 vaccines, which saved millions of lives, and the researchers have already proposed a fix that may help make future vaccines or drugs based on mRNAs safer and even more effective.
LOL! Trust us that the fact that there is an over 30% chance that your body made the wrong protein because the mRNA technology that you injected yourself with over and over and over was inherently flawed is actually a GOOD THING! Thank the Lord for this inherently flawed mRNA delivery platform that can only do good and could never possibly do any harm!
... “some of the future wider therapeutic uses for RNA technology beyond vaccines may involve higher and more frequent dosing, so any and all possible issues need to be addressed.”
But trust us, the 7 injections that we already forced you to get were totally awesome!!! We're Science! Don't you trust Science?
Strands of mRNA convey the blueprints encoded in cells’ genes to their protein-making machinery called ribosomes. The ribosomes read mRNA three bases at a time, with each of these so-called codons specifying an amino acid in the protein. Potential mRNA vaccines and therapies consist of artificial mRNA that carries the recipe for a specific protein. For vaccines, the goal is to generate an immune response to the protein—the spike protein of the pandemic coronavirus, for example. mRNA therapeutics aim to coax a person’s own cells to produce a protein that can treat a disease.
But because foreign RNA usually means a virus is attacking, cells tend to recognize and destroy it. Katalin Karikó and Drew Weissman of the University of Pennsylvania decades ago discovered that if they altered one of mRNA’s bases, replacing uridine with pseudouridine, the modified strand could elude destruction long enough for cells to make the intended protein. The research, for which they will receive Nobel Prizes on Sunday in Sweden, helped accelerate the development of potential mRNA vaccines and therapies.
Unfortunately, this inherently flawed technology doesn't actually work in over 30% of cases, but don't worry! We only awarded the inventors of this inherently flawed technology a Nobel Prize to reduce vaccine hesitancy anyway!
However, the new work finds that the RNA modification strategy has a catch.
LOL! Don't you know, there is always "a catch"?
University of Cambridge toxicologists Anne Willis and James Thaventhiran and their colleagues wondered what effect the pseudouridine might have on the protein-making process. Ribosomes sometimes translate natural mRNAs incorrectly, and the researchers wanted to know whether such mistakes are more common when altered bases are inserted. They designed mRNAs that would prompt cells in a dish to produce a fluorescent protein only if a ribosome “slips” and starts to read the three-letter codons incorrectly, a mistake known as a frameshift. With natural mRNAs, this typically produces inactive proteins that are broken down by the cell.
The researchers found that mRNAs containing the form of pseudouridine used in Pfizer’s and Moderna’s COVID-19 vaccines were much more likely to induce frameshifted proteins than mRNAs with normal uridines. In their experiments, roughly 8% of the proteins produced from their experimental mRNAs were frameshifted.
To test whether the same effect happens in the body, the team compared the immune reactions of mice that were vaccinated either with the COVID-19 mRNA vaccine made by Pfizer or with a less widely used DNA-based vaccine from AstraZeneca. They found that the Pfizer-vaccinated mice generated antibodies to frameshift-derived proteins, whereas animals vaccinated with the AstraZeneca vaccine did not.
The researchers then examined immune responses in 20 people who got the AstraZeneca vaccine and 21 who got the Pfizer vaccine. Blood samples from about one-third of the Pfizer recipients showed an immune reaction to the frameshifted proteins, whereas none of the samples from AstraZeneca recipients did. None of the people reported any side effects from their particular vaccine, and there is no evidence, the researchers say, that the frameshifted protein is harmful.
But all of this is actually a good thing! Please remember to trust us! We are Science, after all!!
The Cambridge team emphasized at a press briefing that its work doesn’t indicate COVID-19 vaccines are unsafe. Indeed, Karikó notes that frameshifts frequently occur naturally when infected cells make viral proteins. These frameshifted proteins can naturally broaden the body’s immune response, she says, so it’s possible that the spike-targeting COVID-19 vaccines may even get a boost from the misreading.
Yes, all of this is definitely a good thing! Please remember to trust us! We are Science, after all!!
When asked about the new paper, Pfizer did not directly comment on its findings but in a statement said its vaccines had a “positive benefit-risk profile.” A Moderna spokesperson declined to comment.
Wait a minute! Why aren't these marketing departments leaping on this OBVIOUSLY GREAT NEWS to sell more of these TOTALLY AWESOME INJECTIONS???
But Thaventhiran says frameshifting might be more important in other applications of mRNA technology such as cancer vaccines, designed to trigger immune responses to tumor-specific proteins. Cancer patients are likely to have received other treatments that alter their immunity, so they might be more vulnerable to the mistaken proteins and any immune reactions they could trigger.
Oh, so, this is not actually great news for all of the other mRNA vaccines that these manufacturers have in the testing and production pipeline. Well, at least it's still great news for the billions that they already sold us! Don't you trust Science?
