Iamwhomiam wrote:slomo wrote:
I have a few bones to pick here, out of an interest in precision.
compared2what? wrote:
Pharma is evil, corrupt, dishonest, criminal and dangerous.
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And, as far as I'm concerned, it is such a a blanket statement that it should not be accepted in its entirety without serious qualification, anyway.
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As someone in the business, somewhat tangentially but still close enough to observe what goes on regularly, I would say that the standards are taken very seriously and adhered to much of the time. The "abundant proof" consists of a few high-profile egregious cases along with meta-analysis that documents the usual failings of all scientific research, namely publication bias that results from a reward system that penalizes null results, as well as routine conflicts-of-interest which, at least from an institutional perspective, are taken seriously. I'm not saying the business is pristine - far from it - but if we are being precise then it stands to reason that we need to take pains not to oversimplify and demonize.
slomo, with all due respect, "much of time time" is simply inadequate, especially in this relation to pharmacological research and human testing, perhaps even grossly so.
Unless people like you, researchers on the inside come forward and reveal those failings, we on the outside pay the price and remain oblivious until tragedy strikes. And you seem to have excluded the true objects of your research, the human patient. But it is fair for you to report from your limited area of experience behind the scene, in the lab.
And to say that c2w? has oversimplified and demonized an industry that kills, maims and institutionalizes many people while seeking a better solution is unfair. There is plenty of anecdotal evidence and many, not a few, well documented "high-profile egregious cases." Of course there could be many more well known egregious cases if only the big pharma didn't demand non-disclosure in their settlement with those they've harmed or their survivors. After all, their primary purpose is not healing patients, but profiting from maintaining them on their drug.
As far as the practice of medicine goes, and I speak only from my own experience, it's atrocious. Yes, there are good doctors, but the profession (I use that word reluctantly) too often defends bad doctors rather than cast a cloud on their profession by ousting them.
And let's not forget or a moment that medicine is a "practice." Some do practice better than others. And some lie and some cheat.
I've had horrible experiences with most of the doctors I've dealt with throughout my life. Having some understanding of medicines and proper treatment of patients, (I studied to become a nurse), makes dealing with uniformed doctors even scarier than it does for one from the general population.
Recently, in December, a friend suffered a series of three unrelated ischemic strokes and wasn't administered heparin for 19 days into his hospitalization, after he had suffered yet another. Because his epiglottis and larnyx had been paralyzed his ability to swallow and his speech was negatively affected. He was given a tracheotomy and put on a ventilator and was receiving nutrition intravenously and via a naso-gastric tube. Years before he had undergone a Whipple surgical procedure and later developed diabetes and afterward also suffered from several hernias. Because of this his doctors at first decided it was best to stay away from compounding his troubles by surgically implanting a feeding tube where his duodenum had been and stick wtih the NG tube. But for some odd reason after his last stroke they decided to go there. During the procedure they hadn't noticed they had ruptured his intestine until the next day when his became septic with a raging fever. This is a teaching hospital and a local trauma center. Needless to say, he won't need to worry about his kids being provided for after his passing.
Another suit dealing with the maltreatment of another patient treated by this institution was just settled for a few million. He had a non-cancerous brain tumor removed and was released with a high temperature suffering from pneumonia.
Questionably, my own worst experience was when I broke my back. I suffered a double spondylolitshesis with a 40% anterior shift and three crushed discs. I was never told I had severely broken my back and he released me to return to my job as a structural steel ironworker. It was only some three years later that the insurance company's doctor explained that I had not strained my back when I was injured, as I had believed.
Oddly enough, During the time of the Reagan administration I also had tree ribs broken at the annual meeting of the American Medical Association, when I entered the assembly hall through the wrong door with an invited guest. ( to be fair, I did have a hoard of angry elderly folks with me, all wearing surgical masks and waving their four-footed canes in the air. Being an organizer, we were there to protest the AMA's support of Reagan's budget. We had already mobbed the main entrance when I had the bright idea of finding an alternative entrance. I did. It was a side entrance down in front, right by the physician studded dais. I got nailed; straight-armed by a line-backer security guard)
Lots of doctors suck, but there are a few good doctors. If you ever come across a good one, please let me know.
I can't presume to argue with your own bad experiences. However, I have had great doctors (although I admit I have not needed much medical attention, comparatively, and will concede that early in my childhood I received some bad medical advice that my family and I avoided heeding). My ex-partner's life was saved by cutting edge medical treatments, treatments that would not be available without and R&D process that I feel is being mischaracterized at the moment. A close family member is now suffering profusely because of a bad medical decision, but I am keenly aware that the decision was made with the best available information at the time. We forget that it is easy to look back in hindsight, with more information, and say what should have been done, but in the moment when split-second decisions must be made, physicians often do their best under fairly significant systemic stresses. So I really have to disagree with the blanket statement.
If you want to argue that pharma pushes drugs inappropriately and has attempted to create a system where pharmaceuticals are the first course of action in any medical situation, no matter how trivial - I will sign my name to that. If you want to argue that medical research can be corrupt, I will agree. If you want to argue that we as a society would be better off looking at prevention, at creating a socioeconomic system that allows people to lead balanced lives with adequate rest and nutrition free from toxic exposures and occupational dangers, I will completely sign off on that. But I don't think it's appropriate to condemn an entire profession filled with people who sought out in life to alleviate suffering, and who toil under great pressures in order to achieve admittedly mixed results.
I should mention that most of my knowledge comes from cancer research where - let's face it - the odds of improving outcomes at least somewhat are reasonably high (owing to the dismal prognosis if the disease is left untreated, for most cancers). Psychiatry is a whole other ball of wax.